Doctoral thesis researches and analyzes systems of computer-based knowledge control as well as work out general principles for designing and formation basing on methods of organization of computer-based knowledge control and assessment estimation models. The main attention is drawn to doing following sum: analyzing existing systems and programs of computer-based knowledge control, studying the problems of organizing and leading knowledge control, systemization and classification of models and methods of computer-based knowledge control, analyzing the models and methods of testing students’ knowledge with aim to formulate suggestions for well-grounded designing and formation of system of computer-based knowledge control.