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Publikācija: Influence of Different Origin Calcium Oxides on Properties of Synthesized Calcium Phosphate Biomaterials

Publication Type Conference paper
Funding for basic activity Unknown
Defending: ,
Publication language English (en)
Title in original language Influence of Different Origin Calcium Oxides on Properties of Synthesized Calcium Phosphate Biomaterials
Field of research 2. Engineering and technology
Sub-field of research 2.5 Materials engineering
Authors Kristīne Šalma-Ancāne
Līga Bērziņa-Cimdiņa
Ņina Mironova-Ulmane
Keywords calcium phosphates, synthesis, biogenic calcium oxide
Abstract In the present study, we investigated a number of calcium oxide containing biogenic (natural) and inorganic materials as reagents for synthesis of calcium phosphates (hydroxyapatite) by modified wet chemical precipitation route. Biogenic materials that are common in nature – eggshells and land snail shells (Arianta arbustorum) and commercially available synthetic calcium oxides were used as calcium oxide sources. The complex investigations of calcium oxide starting materials and synthesized calcium phosphate products were made. Hydroxyapatite bioceramics obtained from CaO of different origins, significant differences in microstructure and color changes after thermal treatment were observed. The different microstructures of hydroxyapatite bioceramics can also significantly influence mechanical properties and bioactivity of materials. Chemical analysis by ICP-MS and FE-SEM/EDS of synthesized products showed different amounts of the microelements Mn, Zn, Cu, Sr, Cd, Pb, Ba as well as trace element Mg. Requirements of International Standard ISO 13779-4 concerning limits of heavy metals which may directly influence biocompatibility of the synthesized product for medical application were checked. It should be considered that the microstructure parameters of obtained bioceramics were influenced by presence of specific trace elements in hydroxyapatite structure, which significantly influenced crystal lattice parameters. Color changes of hydroxyapatite bioceramics after thermal treatment are most likely caused by oxidation of transition elements located in crystal lattice. Considering that Mn concentration in all hydroxyapatite products was higher than that of other transition elements, it should be noted that white → light blue → dark blue color transition appeared as a result of [Mn2+] ions oxidizing to [Mn5+] ions at 700ºC and 1200ºC in ambient atmosphere. Systematic research has proven that origin of the calcium oxides bring a significant impact on the properties and quality of bioceramic implants and can affect biocompatibility and bioactivity of these materials.
Reference Šalma-Ancāne, K., Bērziņa-Cimdiņa, L., Mironova-Ulmane, Ņ. Influence of Different Origin Calcium Oxides on Properties of Synthesized Calcium Phosphate Biomaterials. In: Euro Bio-Inspired Materials: International School and Conference on Biological Materials Science: Book of Abstracts, Germany, Potsdam, 20-23 March, 2012. Potsdam: Deutsche Gesellschaft fuer Materialkunde e.V., 2012, pp.31-31.
ID 13884