Personalized Therapy Selection by Using Multi-objective Optimization

Proceedings of 16th International Conference on Intelligent Engineering Systems (INES 2012) 2012
Ivars Karpičs

In the article a therapy selection method by using topological modelling and multi- objective optimization is presented. In a medicine practice a doctor by taking into the count patients’ health state and laboratory results, tries to suggest a treatment strategy, which mostly is a drug therapy. To solve this task a decision support system has been developed and proposed. The system includes a mathematical model of three self connected diseases. Therapies are evaluated by five efficiency objectives. To find the optimal therapy, seven multi- objective methods are selected and used. Optimization methods form decision support module which is implemented in the medical computer system. To evaluate a performance of the system, test examples are analysed. Conclusion includes the summary and proposals of further research.

Keywords
Topological modeling, graphs, multi-objective optimization
DOI
10.1109/INES.2012.6249893
Hyperlink
http://ieeexplore.ieee.org/document/6249893/

Karpičs, I. Personalized Therapy Selection by Using Multi-objective Optimization. In: Proceedings of 16th International Conference on Intelligent Engineering Systems (INES 2012), Portugal, Lisbon, 13-15 June, 2012. Piscataway: IEEE, 2012, pp.537-542. ISBN 978-1-4673-2694-0. e-ISBN 978-1-4673-2693-3. Available from: doi:10.1109/INES.2012.6249893

Publication language
English (en)