The Mukaiyama Reagent: An Efficient Condensation Agent
Synlett 2013
Irina Novosjolova

The Mukaiyama reagent (2-chloro-1-methylpyridinium iodide, CMPI) is one of the most valuable reagents for ­activation of hydroxyl groups of carboxylic acids and ­alcohols. It is a pale yellow crystalline solid which is stable at room temperature in closed containers under normal storage and handling conditions. CMPI is commercially available, but can be easily synthesized from 2-chloro­pyridine and methyliodide.


Keywords
Mukaiyama reagent, 2-chloro-1-methylpyridinium iodide, CMPI
DOI
10.1055/s-0032-1317530

Novosjolova, I. The Mukaiyama Reagent: An Efficient Condensation Agent. Synlett, 2013, 24, pp.135-136. e-ISSN 1437-2096. ISSN 0936-5214. Available from: doi:10.1055/s-0032-1317530

Publication language
English (en)
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