Since today's enterprises must constantly adapt to rapidly changing external environment, it is necessary to be able to deal with variation and changing conditions in information systems (IS) development. This may be achieved by the use of multifractal IS development methodologies. Fractal approaches to some extent have already been tested in adaptive enterprise development, adaptive manufacturing systems development, and software development. This suggests that multifractal IS development, on the one hand, is appropriate, because the information system should properly reflect the business enterprise (in this case a fractal one) and, on the other hand, it is possible, because some elements of it have already been implemented. Development of multifractal IS aims at managing relative completeness by relative simplicity that has to be discovered in different subsystems that influence the development of the information system. This, in essence, implies the need of thorough analysis an understanding of business structures and processes to discover patterns useful for the identification of fractal features. Currently, only some guidelines for development of multifractal IS are derived from reported experiences of fractal systems development and the use of fractal approaches in other domains.