The paper is devoted to the analysis of aggregated and disaggregated manufacturing sector development tendencies in Latvia and the elaborated long-term development forecasts of the manufacturing sector, using the Latvian multisectoral macroeconomic model. The author presents a brief description of Latvian multisectoral macroeconomic model. The recommendations and solutions are presented to improve and to further promote disaggregated modeling of sub-branches of manufacturing sector in Latvia.