Synthesis and Reactions of 2,6-Diazidopurine Deoxynucleoside

Proceedings of Scientific Conference "Organic Chemistry" 2013
Kristers Ozols, Ērika Bizdēna

In recent years number of novel 1,2,3-triazolylpurine nucleosides have been synthesized including compounds with biological activity: adenosine receptor antagonists and agonists, anticancer and antiviral agents. In this research synthesis of 2,6-bistriazolyl deoxynucleosides in Cu catalysed 1,3-dipolar azide-alkyne cycloaddition reaction (Click reaction) has been investigated.

Keywords
Purine nucleosides, Deoxyribonucleosides, "Click" reaction

Ozols, K., Bizdēna, Ē. Synthesis and Reactions of 2,6-Diazidopurine Deoxynucleoside. In: Proceedings of Scientific Conference "Organic Chemistry", Lithuania, Kaunas, 24-24 April, 2013. Kaunas: 2013, pp.21-21.

Publication language
English (en)