Publication Type |
Scientific article indexed in SCOPUS or WOS database
|
Funding for basic activity |
Unknown
|
Defending: |
, |
Publication language |
English (en) |
Title in original language |
5-Alkyl and 5,5-Dialkyl Meldrum’s Acids |
Field of research |
1. Natural sciences |
Sub-field of research |
1.4 Chemical sciences |
Authors |
Inese Mieriņa
|
Keywords |
5-Alkyl and 5,5-Dialkyl Meldrum’s Acids |
Abstract |
5-Alkyl and 5,5-dialkyl Meldrum’s acids (1 and 2, respectively) are used in total synthesis.[1] Monoalkylated derivatives 1 are synthesized from Meldrum’s acid 3 by condensation with aldehyde[2] (or by acylation[3]) followed by hydrogenation.
5,5-Dialkyl Meldrum’s acids 2 can be obtained by alkylation of Meldrum’s acid 3 or its monoalkylated derivatives 1 (Scheme [1]).[4] Herein, reactions of Meldrum’s acids 1 and 2 proceeding with destruction of 1,3-dioxane cycle are reviewed.
|
DOI: |
10.1055/s-0033-1340156 |
Hyperlink: |
https://www.thieme-connect.de/ejournals/html/10.1055/s-0033-1340156  |
Reference |
Mieriņa, I. 5-Alkyl and 5,5-Dialkyl Meldrum’s Acids. Synlett, 2014, Vol.25, Iss.1, pp.155-156. ISSN 0936-5214. e-ISSN 1437-2096. Available from: doi:10.1055/s-0033-1340156 |
Additional information |
Citation count:
|
ID |
17313 |