On Differences between Racemic and Enantiomerically Pure Forms of Aziridine-2-carboxamide

ChemInform 2013
Māris Turks, Inese Rijkure, Sergejs Beļakovs, Daina Zicāne, Viktors Kumpiņš, Ērika Bizdēna, A. Meikas, A. Valkna

A straightforward, reproducible and scalable method for the synthesis of both enantiomers of aziridine-2-carboxamide (Leakadine) is described.

Keywords
aziridine derivatives; diastereoselective syntheses, enantioselective syntheses (incl. cis/trans-isomerism); pharmacology, medicinal chemistry, vaccines, serums
DOI
10.1002/chin.201306058
Hyperlink
http://onlinelibrary.wiley.com/doi/10.1002/chin.201306058/abstract

Turks, M., Rijkure, I., Beļakovs, S., Zicāne, D., Kumpiņš, V., Bizdēna, Ē., Meikas, A., Valkna, A. On Differences between Racemic and Enantiomerically Pure Forms of Aziridine-2-carboxamide. ChemInform, 2013, Vol.44, Iss.6, pp.58-58. ISSN 1522-2667. Available from: doi:10.1002/chin.201306058

Publication language
English (en)