Requirements of the information age causes new challenges for universities – necessity to change teaching and learning process to ensure that students be able to interpret non-standardized information for problem solving and decision making and have skills of effective turning their knowledge into action which is a requisite that graduates from universities will be innovative and will become so called knowledge workers. The purpose of the paper is to attract educators’ attention to the potential of getting synergy effect from integration of intelligent tutoring and knowledge assessment systems with personal knowledge management systems. The conceptual framework is based on multiagent paradigm and the novel approach how to support student-centered individualized study process using traditional modules of intelligent tutoring systems (ITSs): tutoring, student diagnosis and domain knowledge modules is described. The conception of graph based pedagogical model is given as well as implementation aspects of two systems (a part of the framework) – the intelligent tutoring system MIPITS and the intelligent knowledge assessment system IKAS are overviewed.