The Exocyclic Olefin Geometry Control via Ireland—Claisen Rearrangement: Stereoselective Total Syntheses of Barmumycin (V) and Limazepine E (VI)

ChemInform 2014
Gints Šmits, Rolands Zemribo

The highly selective Ireland—Claisen rearrangement of seven-membered lactone-derived boron enolate generated in situ is the key step to synthesize the naturally occurring antitumor agents (V) and (VI).

Keywords
other bioactive products;rearrangements
DOI
10.1002/chin.201405218
Hyperlink
http://onlinelibrary.wiley.com/doi/10.1002/chin.201405218/abstract

Šmits, G., Zemribo, R. The Exocyclic Olefin Geometry Control via Ireland—Claisen Rearrangement: Stereoselective Total Syntheses of Barmumycin (V) and Limazepine E (VI). ChemInform, 2014, Vol.45, Iss.5, pp.1-1. e-ISSN 1522-2667. Available from: doi:10.1002/chin.201405218

Publication language
English (en)