Synthesis, Studies of Properties and Structure-Activity Relationships of New Delivery Systems based on the Self-Assembling Polyfunctional Pyridinium Derivatives
4th International Conference on Multifunctional, Hybrid and Nanomaterials: Abstract Book
2015
Arkadij Sobolev,
Velta Ose,
Kārlis Pajuste,
Marina Gosteva,
Māra Plotniece,
Klāvs Pajuste,
Martins Rucins,
Brigita Cekavicus,
Brigita Vīgante,
Aiva Plotniece
Polyfunctional pyridinium derivatives on the 1,4-dihydropyridione scaffold possessing self-assembling properties. 1,4-DHP forms liposomes and efficiently acts as gene delivery agent. The influence of lipids head-group on transfection activity and properties of formed liposomes were studied.
Keywords
1,4-DHP, self-assembling, liposomes
Sobolev, A., Ose, V., Pajuste, K., Gosteva, M., Plotniece, M., Pajuste, K., Rucins, M., Cekavicus, B., Vīgante, B., Plotniece, A. Synthesis, Studies of Properties and Structure-Activity Relationships of New Delivery Systems based on the Self-Assembling Polyfunctional Pyridinium Derivatives. In: 4th International Conference on Multifunctional, Hybrid and Nanomaterials: Abstract Book, Spain, Sitges, 9-13 March, 2015. Sitges: 2015, pp.P3.033-P3.033.
Publication language
English (en)