Formation of Calcium-Deficient Hydroxyapatite via Hydrolysis of Nano-Sized Pure Α-Tricalcium Phosphate
Advanced Materials Research 2015
Linda Vecbiškena, Kārlis-Agris Gross, Una Riekstina, Thomas CK Yang

Nano-sized pure α-tricalcium phosphate (α-TCP) fabricated by a novel synthesis approach shows great potential for a faster transformation into calcium-deficient hydroxyapatite (CDHA) than conventionally prepared α-TCP. In this work, amorphous tricalcium phosphate precursors were precipitated and treated with a solvent (water or ethanol), and dried (freeze-dried and oven-dried) before heating at 775 °C. Nano-sized α-TCP powders were investigated for their phase composition and crystallinity, particle shape and size, reactivity and cellular biocompatibility. Reaction with water showed faster CDHA formation for freeze-dried powder, at 6 hours, compared to ethanol treated powders, whereas a higher biocompatibility was found for pure α-TCP.


Keywords
Amorphous calcium phosphate, α-tricalcium phosphate, calcium-deficient hydroxyapatite, cell response
DOI
10.4028/www.scientific.net/AMR.1117.201
Hyperlink
https://www.scientific.net/AMR.1117.201

Vecbiškena, L., Gross, K., Riekstina, U., CK Yang, T. Formation of Calcium-Deficient Hydroxyapatite via Hydrolysis of Nano-Sized Pure Α-Tricalcium Phosphate. Advanced Materials Research, 2015, Vol. 1117, pp.201-204. ISSN 1022-6680. e-ISSN 1662-8985. Available from: doi:10.4028/www.scientific.net/AMR.1117.201

Publication language
English (en)
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