Self-Assembling Cationic Pyridine Derivatives NAD/NADH Analogues as Gene Deliverysystems: Biological and Physicochemical Properties
Drug Discovery Conference: Abstract Book
2015
Kārlis Pajuste,
Martins Rucins,
Oksana Petricenko,
Aleksandra Vezane,
Irena Timofejeva,
Marina Gosteva,
Klāvs Pajuste,
Māra Plotniece,
Brigita Cekavicus,
Brigita Vigente,
Tatjana Kozlovska,
Arkadij Sobolev,
Aiva Plotniece
Polyfunctional pyridinium derivatives on the 1,4-DHP scaffold possess self-assembling properties. 1,4-DHP deerivatives form liposomes and efficiently act as gene delivery agents. the influence of lipids head-group on transfection activity and properties of formed liposomes were studed.
Keywords
SELF-ASSEMBLING CATIONIC PYRIDINE DERIVATIVES, GENE DELIVERY
Hyperlink
http://www.innovabalt.eu/pictures/zinas/225.pdf
Pajuste, K., Rucins, M., Petricenko, O., Vezane, A., Timofejeva, I., Gosteva, M., Pajuste, K., Plotniece, M., Cekavicus, B., Vigente, B., Kozlovska, T., Sobolev, A., Plotniece, A. Self-Assembling Cationic Pyridine Derivatives NAD/NADH Analogues as Gene Deliverysystems: Biological and Physicochemical Properties. In: Drug Discovery Conference: Abstract Book, Latvia, Rīga, 27-29 August, 2015. Rīga: 2015, pp.131-131.
Publication language
English (en)