Alkylidene and Arylidene Meldrum's Acids as Versatile Reagents for the Synthesis of Heterocycles

Chemistry of Heterocyclic Compounds 2016
Inese Mieriņa, Māra Jure

Meldrum`s acid and its derivatives are excellent building blocks for synthesis of acyclic, carbocyclic and heterocyclic compounds.1 Herein recent (mainly year 2011 to 2015) trends on applications of arylidene/alkylidene Meldrum`s acid 1 (R1, R2 = H, Ar, Alk, -(CH2)n-) in the synthesis of heterocycles, and multicomponent reactions (MCR) involving their formation in situ are focused.

Keywords
arylidene Meldrum`s acid, alkylidene Meldrum`s acid, 5-arylidene-2,2-dimethyl-1,3-dioxan-4,6-dione, 5-alkylidene-2,2-dimethyl-1,3-dioxan-4,6-dione, multicomponent reaction
DOI
10.1007/s10593-016-1822-x
Hyperlink
http://link.springer.com/article/10.1007%2Fs10593-016-1822-x

Mieriņa, I., Jure, M. Alkylidene and Arylidene Meldrum's Acids as Versatile Reagents for the Synthesis of Heterocycles. Chemistry of Heterocyclic Compounds, 2016, Vol.52, No.1, pp.7-9. ISSN 0009-3122. e-ISSN 1573-8353. Available from: doi:10.1007/s10593-016-1822-x

Publication language
English (en)