The appearance on the market of compact Stirling electrical coolers opens up the development prospect of wide range of nuclear-physical equipment based on semiconductor detectors (SCD) using such electrical coolers. The main problem in this task is the presence of mechanical vibrations in electrical cooler which considerably influence energy resolution of the SCD. This paper presents an overview of the different types of electrical coolers, suitable for cooling the SCD, analysis of their advantages and disadvantages to solve specific task on gamma-spectrometric equipment development. Particular attention is given to the vibration characteristics of electrical coolers, depending on their design (simple Stirling cycle, pulse tube...), and cooling power. Results of SCD’s cooling system computer simulation based on electrical coolers, spectrometric devices development results with their application for a nuclear energetics, inspection control and space are presented.