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Publikācija: In Vitro Biocompatibility of Si Alloyed Multi-Principal Element Carbide Coatings

Publication Type Scientific article indexed in SCOPUS or WOS database
Funding for basic activity Unknown
Defending: ,
Publication language English (en)
Title in original language In Vitro Biocompatibility of Si Alloyed Multi-Principal Element Carbide Coatings
Field of research 1. Natural sciences
Sub-field of research 1.3 Physical sciences
Authors Alina Vladescu
I Titorencu
Jurijs Dehtjars
V Jinga
V Pruna
M Balaceanu
M Dinu
I Pana
Viktorija Vendiņa
M Braic
Abstract This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.In the current study, we have examined the possibility to improve the biocompatibility of the (TiZrNbTaHf)C through replacement of either Ti or Ta by Si. The coatings were deposited on Si and 316L stainless steel substrates by magnetron sputtering in an Ar+CH4 mixed atmosphere and were examined for elemental composition, chemical bonds, surface topography, surface electrical charge and biocompatible characteristics. The net surface charge was evaluated at nano and macroscopic scale by measuring the electrical potential and work function, respectively. The biocompatible tests comprised determination of cell viability and cell attachment to the coated surface. The deposited coatings had C/(metal+Si) ratios close to unity, while a mixture of metallic carbide, free-carbon and oxidized species formed on the film surface. The coatings' surfaces were smooth and no influence of surface roughness on electrical charge or biocompatibility was found. The biocompatible characteristics correlated well with the electrical potential/work function, suggesting a significant role of surface charge in improving biocompatibility, particularly cell attachment to coating's surface. Replacement of either Ti or Ta by Si in the (TiZrNbTaHf)C coating led to an enhanced surface electrical charge, as well as to superior biocompatible properties, with best results for the (TiZrNbSiHf)C coating.
DOI: 10.1371/journal.pone.0161151
Hyperlink: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0161151 
Reference Vladescu, A., Titorencu, I., Dehtjars, J., Jinga, V., Pruna, V., Balaceanu, M., Dinu, M., Pana, I., Vendiņa, V., Braic, M. In Vitro Biocompatibility of Si Alloyed Multi-Principal Element Carbide Coatings. PLoS ONE, 2016, Vol.11, Iss.8, pp.1-18. ISSN 1932-6203. Available from: doi:10.1371/journal.pone.0161151
Additional information Citation count:
ID 23027