Synthesis of Chiral Phosphazene Bases

Chemistry of Heterocyclic Compounds 2016
M. Priede, E. Priede, J. Saame, I. Leito, Edgars Sūna

Air-stable and crystalline tetraaminophosphonium tetrafluoroborates possessing chiral, enantiomerically pure 1,2-diamine moiety have been synthesized by a three-step sequential one-pot approach. The tetrafluoroborate salts can be purified by recrystallization or chromatography and subsequently converted to the phosphazene bases by treatment with t-BuOK. Basicity values in tetrahydrofuran have been measured for the obtained phosphazene bases by means of spectrophotometric titration.

Keywords
basicity | one-pot synthesis | phosphazene bases | pK value ip | tetraaminophosphonium salts
DOI
10.1007/s10593-016-1927-2
Hyperlink
http://link.springer.com/article/10.1007/s10593-016-1927-2

Priede, M., Priede, E., Saame, J., Leito, I., Sūna, E. Synthesis of Chiral Phosphazene Bases. Chemistry of Heterocyclic Compounds, 2016, Vol.52, Iss.8, pp.541-545. ISSN 0009-3122. e-ISSN 1573-8353. Available from: doi:10.1007/s10593-016-1927-2

Publication language
English (en)