Joint usage of frames and Topological Functioning Model (TFM) provides proper analysis of knowledge in the domain under study. The main issue in domain knowledge analysis is completeness of discovered knowledge. Formal representation of the knowledge in frames allows automated construction and validation of the TFM, thus allowing to discover white places in knowledge. Analysing TFM metamodels, the structure of the frame system for generation of the TFM is proposed. The frame system leads to highlighting structural knowledge, while validation of the generated TFM shows white places in behavioural knowledge. Validation of the TFM does not guarantee the complete identity of obtained knowledge to the domain, since the knowledge is based on expert opinions. Thus, analysis of the problem domain is shifted from the separate investigation of dynamic and structural aspects of the system to holistic understanding of domain phenomena. The presented results should be refined if other derived models are added.