Cytotoxicity, Self-Assembling and Physico-Chemical Properties of Bifunctional Lipid-like 4-(N-Alkylpyridinium)-1,4-Dihydropyridines as Putative Delivery Systems

Intrinsic Activity 2017
Pavels Dimitrijevs, Martins Rucins, Oksana Petrichenko, Māra Plotniece, Anita Gulbe, Ludmila Jackevica, Marina Gosteva, Dace Bandere, Ilona Domracheva, Kārlis Pajuste, Arkadij Sobolev, Aiva Plotniece

Design of biologically active delivery materials is an ideal strategy for biomedical applications. Previously, cationic 1,4-DHP amphiphiles capable of transfecting pDNA into cell lines in vitro were developed.

Keywords
cytotoxicity, synthetic lipids, nanoparticles, dynamic light scattering
DOI
10.25006/IA.5.S2-A2.4
Hyperlink
http://www.intrinsicactivity.org/2017/5/S2/A2.4/

Dimitrijevs, P., Rucins, M., Petrichenko, O., Plotniece, M., Gulbe, A., jackevica, L., Gosteva, M., Bandere, D., Domracheva, I., Pajuste, K., Sobolev, A., Plotniece, A. Cytotoxicity, Self-Assembling and Physico-Chemical Properties of Bifunctional Lipid-like 4-(N-Alkylpyridinium)-1,4-Dihydropyridines as Putative Delivery Systems. Intrinsic Activity, 2017, Vol.5, Suppl.2, pp.A.2.4-A.2.4. ISSN 2309-8503. Available from: doi:10.25006/IA.5.S2-A2.4

Publication language
English (en)