The lands inhabited by the Balts on the Baltic Sea coast were visited by representatives of neighbouring people long time ago, and building traditions developed due to interaction of different cultures. Wooden buildings on castle mounds built by local people were replaced by masonry fortresses built by strangers, and in their neighbourhood urban settlements with merchants and craftsmen’s houses emerged. The first cities were founded, where the biggest part of low-rise building was covered by residential wooden buildings typical of rural environment, adapted gradually to urban planning requirements. Wooden buildings in the second half of the 18th century obtained a monumental appearance, but building in Latvian ethnographic regions in Courland, Semigallia, Vidzeme and Latgale – singularity of architectonic forms, whose expressivity was determined by scale and relations of spatial structures. Building of towns merged perfectly with the landscape: relief, waters and greeneries awarded it with own identity. In the 19th century urban building was functionally supplemented with different public buildings. Due to interaction of nature and human activities in Latvia regional cities during centuries a qualitative architectonic space was created, which manifests the local inhabitants’ attitude to art and architecture, what during the long development course has formed its own characteristic language – relation system of common signs and symbols in order to reflect the most profound essence of the creative expression. In architecture the message is never neutral – it has its intrigue. When looking for harmony in the interaction of new and historical building through movement, development and contradictions, dialectics of architectonic forms are clearly manifested. In the dynamically changing and information overloaded world proportions and scale of bulky spatial structures fully comply with economic requirements, but events and phenomena are assessed by each of us according to our own knowledge and impressions about space and time. Particular and diverse environment is necessary for personal development, where a human being, expressing an active attitude to neighbourhood, could cultivate their creative abilities in the interaction of life experience and information. In regional architecture of the restored Republic of Latvia relations of forms are perceived in landscape and architectonic context. In regional towns in the environment created by diverse architectonic forms an open space correlates with a closed or partly closed space, and synthesis of natural and architectonic forms has become a brand , which promotes original spatial composition and development of planning. The silhouette and structural architecture of construction volume are parts of informatively the most spacious and emotionally the most active spatial environment, which enables us to perceive the spatial form of the building more easily. In Latgale natural and building harmony encourages us to look for artistically innovative solutions for cultural enrichment. In the town centre of Rezekne next to the Latgalian mound with castle ruins from Livonian times the building complex of the Eastern Latvian Centre of Creative Services “Zeimuls” has been built, whose roof shapes of the lower construction volume have been matched to the relief of the mound, but its buildings contrast with the surrounding houses, which remind of sculptures, whose silhouettes can been seen in landscape and sky background. The plastic architecture of the construction site is clearly revealed in chiaroscuro, heterogeneity and dynamics of the spatial structure, providing all of us with a semantic message. Goal of the paper: analyse interaction of ancient and modern regional architecture in Rezekne, applying object observation in nature, photo fixations and graphic materials, analize the correlation of R'ezekne's ancient and modern architecture, impact of solutions of the earlier ageson the modern urban planning and architectural development. Theoretical research methods: the comparative method is the main one in the research, which gives an opportunity to obtain general and particular conclusions. The logical method or analogous conclusion has also been applied.