In(III) and Hf(IV) Triflate-Catalyzed Hydration and Catalyst-free Hydrohalogenation of Aryl Acetylenes in Liquid Sulfur Dioxide

ACS Omega 2018
Krista Gulbe, Māris Turks

The use of liquid sulfur dioxide as a reaction solvent to promote chemical transformations of alkynes has been explored. First, a combination of liquid SO2 and In(OTf)3 or Hf(OTf)4 as a catalyst allows to perform hydration of aryl alkynes under mild conditions without a direct addition of Brønsted acid. Second, novel catalyst-free conditions for the synthesis of α-vinyl iodides, bromides, and chlorides from aryl alkynes have been developed in liquid SO2 using group I and II metal halides and ammonium iodide as the halide ion sources.

Keywords
In(III) and Hf(IV) Triflate-Catalyzed Hydration Catalyst-free Hydrohalogenation Aryl Acetylenes Liquid Sulfur Dioxide
DOI
10.1021/acsomega.8b01630
Hyperlink
https://pubs.acs.org/doi/10.1021/acsomega.8b01630

Gulbe, K., Turks, M. In(III) and Hf(IV) Triflate-Catalyzed Hydration and Catalyst-free Hydrohalogenation of Aryl Acetylenes in Liquid Sulfur Dioxide. ACS Omega, 2018, Vol.3 No.12, pp.18065-18077. e-ISSN 2470-1343. Available from: doi:10.1021/acsomega.8b01630

Publication language
English (en)