Reactions of Isatoic Anhydride with Diamines
2008
Fricis Avotiņš, Ērika Bizdēna, Inta Strakova, Andris Strakovs

In reactions of isatoic anhydride with diamines – 1,3-diamino-2-hydroxypropane, 4,4’-diaminodiphenylmethane, 4,4’-diaminodiphenyloxide, 4,4’-diaminodiphenylsulphide, 2,2’-diaminodobenzyle, in molar ratio 2:1, when boiled 3-4 hours in ethanole, corresponding bis-anthranoylaminoderivatives were obtained. Boiling of these compounds with exception of 2,2’-diaminodibenzyle, gave corresponding bis-[4(3H)-quinazolinon-3-yl] derivatives. The synthesized compounds are well soluble in polar organic solvents, stable at melting temperatures crystalline substances. In reaction of 1-(2-aminoethyl)piperazine with isatoic anhydride 1-(2-anthranoylaminoethyl)-4-anthranoylpiperazine was synthesized. 2-Aminobenzylamine with isatoic anhydride in molar ratio 1:1 afford 2-aminobenzylanthranylamide. The structure of obtained compounds are confirmed with 1H-NMR and IR spectra.


Keywords
di(aminoaril)atvasinājumi, di(antranilamīdi), trietoksimetāns, 3-aizvietoti 4(3H)hinazolinoni

Avotiņš, F., Bizdēna, Ē., Strakova, I., Strakovs, A. Reactions of Isatoic Anhydride with Diamines . Materials Sciences and Applied Chemistry. Vol.16, 2008, pp.142-147. ISSN 1407-7353.

Publication language
Latvian (lv)
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