Synthesis of Spiro Compounds Based on Bicyclo[3.3.1]nonane
2011
Linas Labanauskas, Albinas Zilinskas, Sigita Visniakova, Gintaras Urbelis, Olga Gedrimaite, Ricardas Rozenbergas, Andrey Podgursky

Organic compounds with bicyclic structure are important because of their stereochemical features and biological activity. The studies of synthesis of spiro compounds bearing bicyclo[3.3.1]nonane framework were based on bicyclo[3.3.1]nonan-2,6-dione and bicyclo[3.3.1]nonan-2-one. These starting compounds were converted to corresponding α-haloketones and treated with 2-aminoethanethiol using microwave irradiation to give new heterocyclic compounds - spiro[bicyclo[3.3.1]nonan-3-ono-2,2'-thiazolidine] and spiro[bicyclo[3.3.1]nonan-3,7-diono-2,2':6,2‘-dithiazolidine]. The efficient method for 3-bromobicyclo[3.3.1]nonan-2,6-dione synthesis was offered.


Atslēgas vārdi
bicyclo[3.3.1]nonane, spiro-compounds, microwave synthesis, thiazolidine, α-haloketones

Labanauskas, L., Zilinskas, A., Visniakova, S., Urbelis, G., Gedrimaite, O., Rozenbergas, R., Podgursky, A. Synthesis of Spiro Compounds Based on Bicyclo[3.3.1]nonane. Materiālzinātne un lietišķā ķīmija . Nr.23, 2011, 73.-76.lpp. ISSN 1407-7353.

Publikācijas valoda
English (en)
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