Morphogenesis around HAp Bioceramic Implants Loaded with Autologous Mesenchymal Cells after Implantation in Subcutaneous Tissue of Rabbits

Journal of Tissue Engineering and Regenerative Medicine 2012
Inese Čakstiņa, K. Rozenbergs, Jānis Ancāns, Laila Feldmane, Andrejs Skaģers, Vita Šteinberga, Līga Bērziņa-Cimdiņa

Two options for graft substitutes are used: (i) hydroxyapatite (HAp) alone, HAp loaded with mesenchymal cells for replacement of lost bone tissue in maxillofacial and orthopedic surgery. Hystomorphological evaluation of connecting tissue around HAp and HAp with mesenchymal cells was used. Six month post implantations, samples were collected and histological protocol using staining with hem/eoz and Machson trichrome was performed. Two layer capsule formation was observed around HAp tablets loaded with cells more intensive as in HAp alone samples.

Atslēgas vārdi
hydroxyapatite, mesenchymal cells, histomorphology
DOI
10.1002/term.1586

Čakstiņa, I., Rozenbergs, K., Ancāns, J., Feldmane, L., Skaģers, A., Zālīte, V., Bērziņa-Cimdiņa, L. Morphogenesis around HAp Bioceramic Implants Loaded with Autologous Mesenchymal Cells after Implantation in Subcutaneous Tissue of Rabbits. Journal of Tissue Engineering and Regenerative Medicine, 2012, Vol.6, Iss.s1, 9.-9.lpp. ISSN 1932-6254. e-ISSN 1932-7005. Pieejams: doi:10.1002/term.1586

Publikācijas valoda
English (en)