Due to the sorption properties of clay minerals clays are widely used in health care as facial masks for treatment of skin inflammations, such as acne, boils and ulcers. Acne is a skin disease, which is thought to be developed by increased production of sebum. Sebum is an oily substance produced by the sebaceous glands located in the skin and it is composed mainly of triglycerides, wax esters, squalene, fatty acids, cholesterol and cholesterol esters. Based on recent research, the skin of acne patients contain 59% more sebum with 2.2 times higher level of squalene. Another skin disease is seborrheic dermatitis, caused mainly by increased level of oleic acid in skin sebum. Most clays used in health care are within the pH range of the skin (pH 5-5.5). Therefore the presence of carbonates causes alkaline conditions, which can be irritating to the skin. Basically all commercial facial clay masks available in Latvia contain illite, which is the abundant clay mineral in Latvia. Neverless, only 3% of these products are made in Latvia. Therefore the aim of this study is to investigate the adsorption of squalene and oleic acid and to evaluate the possibility of application of Latvian clays in health care.