Due to their sorption properties clays are used as facial masks for removal of toxins, excess sebum (secretion of sebaceous glands) and as treatment of skin inflammations. Sebum is a mixture of lipids composed mainly of triglycerides, wax esters, squalene, fatty acids, cholesterol and cholesterol esters. Recent research shows that acne patients have for 59% more sebum with 2.2 times higher level of squalene. Another skin disease is seborrheic dermatitis, caused mainly by increased levels of - oleic acid (a fatty acid). The presence of carbonates causes alkaline conditions, which can be irritating to the skin. Majority of the clays used in cosmetics are within the pH range of the skin (pH 5-5.5). The aim of this study is to evaluate the possibility of application of Latvian clays in cosmetics as active ingredients. Sorption experiments were performed with squalene and two fatty acids (oleic and stearic) in squalane media.