Stereoselective Synthesis of the Diazonamide a Macrocyclic Core
Journal of Organic Chemistry
2015
Ilga Mutule,
Beomjun Joo,
Zane Medne,
Toms Kalniņš,
Edwin Vedējs,
Edgars Sūna
Stereoselective synthesis of the right-hand heteroarom. macrocycle of diazonamide A features C16-C18 bond formation in the Suzuki-Miyaura cross-coupling and atropodiastereoselective Dieckmann-type macrocyclization as key steps. The Suzuki-Miyaura cross-coupling gave the best yields when it was catalyzed by a palladium-dioxygen complex.
Atslēgas vārdi
Stereoselective Synthesis of the Diazonamide A Macrocyclic Core
DOI
10.1021/jo5029419
Hipersaite
http://pubs.acs.org/doi/abs/10.1021/jo5029419
Mutule, I., Joo, B., Medne, Z., Kalniņš, T., Vedējs, E., Sūna, E. Stereoselective Synthesis of the Diazonamide a Macrocyclic Core. Journal of Organic Chemistry, 2015, Vol.80, Iss.6, 3058.-3066.lpp. ISSN 0022-3263. e-ISSN 1520-6904. Pieejams: doi:10.1021/jo5029419
Publikācijas valoda
English (en)