hotocatalytic activity of TiO2 nanoparticles strongly depends on its crystallity, specific surface area, morphology of the particles and used dopants. Promising are materials with high specific surface area and with modified composition. In the present work formation of active TiO2 nanoparticles in microwave synthesis and their modification with sulfur and platinum were studied. Anatase nanopowder and 10M KOH solution were used as raw materials. Microwave assisted synthesis method permited to obtain TiO2 nanofibres and nanowires with a diameter of 10 nm and a specific surface area in the range of 70- 150m2 / g. In order to improve the photocatalytic activity of nanofibers under visible and UV light, the samples were modified by their treatment at 380oC in hydrogen sulfide gas streams for different time intervals. In order to modified TiO2 nanofibers with platinum it was stirred in H2PtCl6 solution under UV irradiation. Photocatalytic activity was determined by degradation of the methylene blue solution under UV and visible light irradiation. The obtained samples showed higher photocatalytic activity with respect to pure TiO2 nanofibers. The doped TiO2 nanofibers were appropriate for degradation of harmful organic compounds as well as for hydrogen production by water splitting.