Benign — A Typical Nevi Discrimination Using Diffuse Reflectance and Fluorescence Multispectral Imaging System
2015 International Conference on BioPhotonics (BioPhotonics)
Early diagnostics of skin cancer is of interest for dermatologists. Atypical nevi are not considered to be malignant, but are suspects that should be detected and monitored over time. The multispectral imaging system Nuance operating in spectral range 450-950 nm was adapted for clinical in vivo measurements in diffuse reflectance and fluorescence mode. Mean and standard deviation values of optical density and fluorescence intensity were extracted from segmented pigmented lesions (21 benign and 26 atypical nevi) and used for further analysis. It was possible to achieve 62% sensitivity and 67% specificity for discrimination between atypical and benign lesions using averaged fluorescence mean intensity and standard deviation values.
Atypical nevi, Autofluorescence, Diffuse reflectance, Multispectral imaging, Skin
Jakovels, D., Saknīte, I., Bļizņuks, D., Spīgulis, J., Kadikis, R. Benign — A Typical Nevi Discrimination Using Diffuse Reflectance and Fluorescence Multispectral Imaging System. No: 2015 International Conference on BioPhotonics (BioPhotonics), Itālija, Florence, 20.-22. maijs, 2015. Piscataway: IEEE, 2015, 1.-4.lpp. e-ISBN 978-1-4673-7926-7. Pieejams: doi:10.1109/BioPhotonics.2015.7304026