Optical Design Improvement for Non-Contact Skin Cancer Diagnostic Device
Proceedings of SPIE 2018
Emilija-Vija Plorina, Dmitrijs Bļizņuks, Alexander Derjabo, Alexey Lihachev, Ilze Lihacova, Ilze Osina, Marta Lange

Multispectral diffuse reflectance imaging and autofluorescence photo-bleaching imaging are methods that have been investigated for use in skin disorder diagnostics. In response to the ever-increasing incidence of skin cancer in light skinned populations a new device has been designed incorporating both of these methods. The aim of the study was to create a device that is most efficient in terms of hardware and software parameters for the screening of malignant and benign skin lesions. The optimal placement in a cylindrical case for a set of 525 nm, 630 nm and 980 nm LEDs that are used to detect diffuse reflectance at three wavelengths [1] as well as a set of 405 nm LEDs used to induce skin autofluorescence [2] was found for a more homogenous illumination of the area of skin being investigated, taking into account the requisite spacing from the camera lens to produce a focused RGB image. The geometrical shape of the device allows to capture images of skin that are illuminated solely by the diodes without interference from sunlight or other nearby light sources. Polarizing filters are used to decrease glare effects, therefore preventing image overexposure of very reflective skin areas, as well as a filter that enables capturing of diffuse reflectance and fluorescence images while blocking fluorescence inducing light. Further improvements to the quality of the diagnostic data can be achieved using reference images to track homogeneity of the intensity and then applying a compensating algorithm on the subsequent screening images. These and other design considerations serve to realize the full potential of the diagnostic method. Results of clinical approbation to assess the efficacy of the new device to diagnose malignant skin lesions will be demonstrated.


Atslēgas vārdi
diffuse reflectance, autofluorescence, skin cancer
DOI
10.1117/12.2307125

Plorina, E., Bļizņuks, D., Derjabo, A., Lihachev, A., Lihacova, I., Osina, I., Lange, M. Optical Design Improvement for Non-Contact Skin Cancer Diagnostic Device. No: Proceedings of SPIE, Francija, Strasbūra, 22.-26. aprīlis, 2018. --: SPIE, 2018, 1.-7.lpp. ISSN 0277-786X. e-ISSN 1996-756X. Pieejams: doi:10.1117/12.2307125

Publikācijas valoda
English (en)
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