In most developing countries and rural areas, water quality remains a serious problem due to potential pollution with a variety of microorganisms, including viruses, faecal coliforms, and protozoa; as well as due to lack in access to improved sanitation. As a result, about 500 000 people die of diarrhoea each year (WHO, 2018). The need for affordable and effective disinfection systems for the improvement of water quality in developing regions is still there. The aim of the present review is to evaluate various commercially available and/or scientifically pointed automated electrochemical systems for water disinfection to establish the most sustainable operation/component setup. The effect of electrode material, electrolyte composition, current intensity, type of tested microorganisms, and bacterial inactivation efficiency have been taken into account in order to demonstrate the advantages and disadvantages of each system.