Synthesis of Novel Lupane-123-Triazole Conjugates and Their Cytotoxicity Evaluation

11th Paul Walden Symposium on Organic Chemistry 2019
Rūdolfs Beļaunieks, Niks Freimanis

Betulin (1) is a naturally occurring pentacyclic triterpene, most commonly found in the birch bark. Research shows that betulin possess wide spectrum of biological activity – anti-inflammatory, antibacterial and anticancer [1]. To improve the latter, structural modifications with new biological activity are being made [2]. This work is devoted for the synthesis of lupane-1,2,3-triazole conjugates for their biological activity evaluation on rare cancer cell lines.

Atslēgas vārdi
Betulīns, Triazoli, Triterpēni

Beļaunieks, R., Freimanis, N. Synthesis of Novel Lupane-123-Triazole Conjugates and Their Cytotoxicity Evaluation. No: 11th Paul Walden Symposium on Organic Chemistry, Latvija, Rīga, 19.-20. septembris, 2019. Rīga: 2019, 29.-29.lpp.

Publikācijas valoda
English (en)