The study investigates energy efficiency performance across 18 main industrial sub-sectors of Latvia in 2017. Acomposite index methodology was applied to develop energy efficiency index (EEI) that consists of 12 differentexplanatory indicators grouped in three main dimensions of energy efficiency–economic, technical, and envi-ronmental. The obtained results highlighted various opportunities for energy efficiency improvement in all thesectors of Latvian manufacturing industry. The results indicate that there is large potential for energy efficiencyimprovements in energy intensive sectors such as wood and non-metallic mineral manufacturing. The funda-mental issues for each sector could be recognized and addressed to the policy makers.