Purine derivatives are widely studied due to their biological activity. Purines containing phoshonate moiety are known as antiviral drugs, representative example is tenofovir [1,2]. In this work C6-phosphonated purine derivatives have been obtained using SNAr-Arbuzov reaction between 2,6-bistriazolylpurine derivatives and phosphites. Staring material 2 was synthesized in two steps using Mitsunobu reaction and substitution of Cl atoms with azides. Then 2,6-diazidopurine derivative 2 was used in CuAAC reactions with different alkynes, giving products 3 in yields up to 76%. Structure and regioselectivity of C6-phosphonated purine derivatives 4 were proved by X-ray analysis