Purine derivatives are widely studied due to their biological activity. They are used as anticancer and antiviral drugs, and as agonists and antagonists of adenosine receptors. 1 In our studies we proved that 1,2,3-triazoles can be used as leaving groups in SNAr reactions with N-, S-, O-, C-nucleophiles. 2-4 In this research we obtained 2,6-bistriazolylpurine derivatives 3 in CuAAC between diazide 2 and different alkyl-/arylalkynes and used them in reactions with phosphites, obtaining 2-triazolylpurine phosphonates 4 in yields up to 82%. Alternative pathway which starts with SNAr-Arbuzov reaction on 2,6-dichloropurine 1, yields phosphonates 5 and involves next SNAr with NaN3 and subsequent CuAAC did not give the desired products 4 (Scheme 1). Structure of compound 4 was proved by X-ray analysis (Scheme 1).