Synthesis of 1,2-Dihydroisoquinoline-1-Carboxylates under Cobalt Catalysis
Chemistry of Heterocyclic Compounds
2021
P.A Zagorska,
Liene Grigorjeva,
Jekaterina Boļšakova
[Figure not available: see fulltext.] A study of cobalt-catalyzed C–H functionalization of phenylglycine derivatives with alkynes is described. During the optimization studies, a range of cobalt catalysts, oxidants, base additives, and reaction solvents were evaluated. Product yield dependence on phenylglycine ester substituent was evaluated. Conditions for 1,2-dihydroisoquinoline synthesis with acceptable yield were found.
Atslēgas vārdi
1,2-dihydroisoquinoline | alkaloids | heterocycles | isoquinoline | phenylglycine
DOI
10.1007/s10593-021-02888-5
Hipersaite
https://link.springer.com/article/10.1007%2Fs10593-021-02888-5
Zagorska, P., Grigorjeva, L., Boļšakova, J. Synthesis of 1,2-Dihydroisoquinoline-1-Carboxylates under Cobalt Catalysis. Chemistry of Heterocyclic Compounds, 2021, Vol. 57, No. 2, 159.-165.lpp. ISSN 0009-3122. Pieejams: doi:10.1007/s10593-021-02888-5
Publikācijas valoda
English (en)