The successful result of restorative and replacement surgical operation depends significantly on properties of used bone cement. Acrylic bone cements are usually based on methylmethacrylate polymer, while monomer polymerization begins after mixing of components in mixing device and terminates in living tissue. Polymerization of methylmethacrylate is exothermic process, and temperature increase might cause tissue necrosis with concomitant implant aseptic loosening. Developed non-ionogenic and containing carboxylic groups of acrylic acid bone cements on the base of poly(methylmethacrylate-2-ethylhexylmethacrylate) – ethylmethacrylate- triethyleneglycol dimethacrylate system have appropriate setting parameters. The influence of polysaccharide nature additive introduction on main properties of developed bone cements has been studied. Starch was used as biocompatible and biodegradable component. The introduction of 20% starch into solid phase of bone cements aroused the change of setting profiles: polymerization peak temperature decreased and setting time increased. The mechanical properties of bone cements determined by pour-point bending and uniaxial compression tests were not worsened by starch introduction. The morphology of fracture of bone cements specimens was studied using electron microscopy. The data obtained testify that bone cements modification with starch additive is perspective for further achieving of bone tissue regeneration.