Hydroxyapatite – HAp [Ca10(PO4)6(OH)2] is widely used as a filling material for bone defects or coating on metallic parts of prosthetic implants due to its biocompatibility and bioactivity. A number of techniques are developed to produce porous materials similar to the natural bone structure. Pores are necessary for bone tissue formation because they allow migration of endothelial cells: to promote vascularisation of mesenchymal cell; or to facilitate osteoblast proliferation and differentiation. The aim of this study was to prepare porous ceramic from synthesized and well characterized hydroxyapatite powder and to examine the stem cells behaviour on this material.