The Ritter Reaction for the Synthesis of Heterocycles

Chemistry of Heterocyclic Compounds 2017
Jekaterina Boļšakova, Aigars Jirgensons

This minireview covers the applications of the Ritter reaction for the construction of different aza-heterocycles published in the time frame from 1988 to 2016. During this period, the Ritter reaction was extensively used for the synthesis of oxazolines, imidazolines, isoindolinones, and other heterocycles. The Ritter reaction was also applied in a series of tandem reactions to produce tetrahydropyrans, piperidines, dihydroisoquinolines, and 1-spiro-2,5-cyclohexadienones.

Keywords
aza-heterocycles; dihydroisoquinolines; imidazolines; isoindolinones; oxazolines; piperidines; 1-spiro-2,5-cyclohexadienones; tetrahydropyrans; Ritter reaction; synthetic methods; tandem reactions
DOI
10.1007/s10593-018-2189-y
Hyperlink
https://link.springer.com/article/10.1007%2Fs10593-018-2189-y

Boļšakova, J., Jirgensons, A. The Ritter Reaction for the Synthesis of Heterocycles. Chemistry of Heterocyclic Compounds, 2017, Vol.53, No.11, pp.1167-1177. ISSN 0009-3122. e-ISSN 1573-8353. Available from: doi:10.1007/s10593-018-2189-y

Publication language
English (en)