Meisenheimer Complexes in Synthesis and Transformations of Azidopurine Derivatives

78th International Scientific Conference of the University of Latvia Chemistry Section: Book of Abstracts 2020
Jānis Miķelis Zaķis, Kristers Ozols

We have observed a sulfonyl group dance when substrate 1 was treated with NaN3. Reaction mechanism and kinetics were investigates using NMR experiments, 15N labelling and FTIR analysis. Current research now focuses on investigation and optimization of purine ring opening reaction.

Keywords
Purine, azide, tetrazole, SNAr, one pot, ring opening

Zaķis, J., Ozols, K. Meisenheimer Complexes in Synthesis and Transformations of Azidopurine Derivatives. In: 78th International Scientific Conference of the University of Latvia Chemistry Section: Book of Abstracts, Latvia, Riga, 6-6 March, 2020. Riga: 2020, pp.56-56.

Publication language
English (en)