In the field of radiation oncology, particle therapy is promising to be more efficient cancer treatment modality due to favorable physical and biological properties over conventional gamma radiation therapy. With shown benefits in treatment of pediatric oncological malignancies, brain and head and neck region tumors and other localizations in vicinity of critical vital organs. The Baltic States remains as one of the only regions in Europe without a dedicated infrastructure for the highly beneficial particle therapy treatment. In the recent years, with the active work of CERN Baltic Group in close collaboration with scientists from Next Ion Medical Machine Study (NIMMS) group of the European Organization for Nuclear Research (CERN), an initiative has been started for an innovative particle therapy center in the Baltic States. Aim To report on the current state of the conceptual design for a novel particle therapy treatment center and research infrastructure proposed by CERN Baltic Group “Advanced Particle Therapy center for the Baltic States” working group and current status of the project overall.