In order to enhance of 3-D polymer structure bone cement biocompatibility, the cement on the base of poly(MMA-hexylacrylate)-ethylmethacrylate-triethyleneglycol dimethacrylate has been modified by the introduction of biodegradable additives. Chitosan and isolated from shrimp exoskeleton chitin were introduced into cement solid phase. The introduction of mentioned additives in studied concentration influences little the temperature profile of cement setting, but increases water uptake and heterogeneity of the cement surface. The introduction of 20% chitosan into cement solid phase practically does not influence bone cement flexural strength and strength in uniaxial compression, but 20% chitin introduction arises the decrease of bone cement ultimate stress and modulus both in flexural tests and uniaxial pressure.