Reactivity Studies of 2,6‐Ditriazolylpurine Nucleosides with Nucleophiles

XX International Roundtable on Nucleosides Nucleotides and Nucleic Acids: Poster Abstracts 2012
Armands Kovaļovs, Irina Novosjolova, Ērika Bizdēna, Māris Turks

Reaction of 2,6-ditriazolylpurine nucleosides with nucleophiles is mild and efficient route to C6 derivatization of purine base. To explore scope and limitations of the method, we studied reactivity of various N- and S-nucleophiles as well as kinetics for selected reactions.

Atslēgas vārdi
ditriazolylpurine nucleosides, 1,3-dipolar cycloaddition reaction, fluorescence, nucleophilic substitution
Hipersaite
http://www.is3na.org/assets/events/Category%203-Nucleos%28t%29ide%20Probes%20%28109-153%29.pdf#page=4

Kovaļovs, A., Novosjolova, I., Bizdēna, Ē., Turks, M. Reactivity Studies of 2,6‐Ditriazolylpurine Nucleosides with Nucleophiles. No: XX International Roundtable on Nucleosides Nucleotides and Nucleic Acids: Poster Abstracts, Kanāda, Montreal, 5.-9. augusts, 2012. [S.l.]: IS3NA, 2012, 112.-112.lpp.

Publikācijas valoda
English (en)