Synthesis of Novel N-Propargyl Substituted 1,4-Dihydropyridene Derivatives as Potential Neuroprotective Agents

Balticum Organicum Syntheticum (BOS2012): International Conference on Organic Synthesis: Program and Abstracts 2012
Kārlis Pajuste, Dainis Kaldre, Linda Klimaviciusa, A. Laizane, M. Vanina, Baiba Skrivele, Kintija Birkmane, Brigita Cekavicus, Māra Plotniece, Martins Rucins, Arkadij Sobolev, Aiva Plotniece, Vija Klusa, Baiba Jansone

Target-directed synthesis is the combination of different moieties is one molecule: pharmacophore propargyl group, cationic moiety and 1,4-dihydropyridine scaffold as a privileged structure.

Atslēgas vārdi
1,4-DHP, neuroprotective agents

Pajuste, K., Kaldre, D., Klimaviciusa, L., Laizane, A., Vanina, M., Skrivele, B., Birkmane, K., Cekavicus, B., Plotniece, M., Rucins, M., Sobolev, A., Plotniece, A., Klusa, V., Jansone, B. Synthesis of Novel N-Propargyl Substituted 1,4-Dihydropyridene Derivatives as Potential Neuroprotective Agents. No: Balticum Organicum Syntheticum (BOS2012): International Conference on Organic Synthesis: Program and Abstracts, Igaunija, Tallinn, 1.-4. jūlijs, 2012. Tallinn: 2012, 152.-152.lpp.

Publikācijas valoda
English (en)