Synthesis of 3-{3-[(4-Methylcyclohex-3-Enyl-Carbonyl)Amino]-4-Oxo-3,4-Dihydroquinazolin-2-Yl}Propanoic Acid Anilides

Chemistry of Heterocyclic Compounds 2012
Daina Zicāne, Irisa Rāviņa, Zenta Tetere, Inese Rijkure

With the aim of discovering potential diuretic agents amongst quinazoline anilides we have prepared anilides of 3-{3-[(4-methylcyclohex-3-enylcarbonyl)amino]-4-oxo-3,4-dihydroquinazolin-2-yl}propanoic acid. Optimal conditions for obtaining of the starting acid have been established, and anilides have been synthesized by the mixed anhydrides method.

Atslēgas vārdi
anilides, hydrazides, mixed anhydrides, propionic acid, quinazolines, succinic anhydride
DOI
10.1007/s10593-012-0997-z
Hipersaite
http://link.springer.com/article/10.1007%2Fs10593-012-0997-z

Zicāne, D., Rāviņa, I., Tetere, Z., Rijkure, I. Synthesis of 3-{3-[(4-Methylcyclohex-3-Enyl-Carbonyl)Amino]-4-Oxo-3,4-Dihydroquinazolin-2-Yl}Propanoic Acid Anilides. Chemistry of Heterocyclic Compounds, 2012, Vol.48, Iss.2, 358.-361.lpp. e-ISSN 1573-8353. ISSN 0009-3122. Pieejams: doi:10.1007/s10593-012-0997-z

Publikācijas valoda
English (en)