Synthesis and Antioxidant Properties of Novel Quinazoline Derivatives

2014
Zenta Tetere, Daina Zicāne, Irisa Rāviņa, Inese Mieriņa, Inese Rijkure

Quinazoline derivatives have expressed a broad spectrum of biological activities, but there are few examples in literature on an antioxidant activity of different quinazolines. On the basis of literature by Chinese scientists on the effective antioxidant activity of Schiff bases containing 2-oxoquinoline and due to structural similarity of quinoline and quinazoline ring systems, the reactions of 3-aminoquinazolinone with a range of aromatic aldehydes and ethoxymethylene derivatives have been carried out and their radical scavenging activities have been studied.

Atslēgas vārdi
3-amino-quinazolin-4(3H)-one, aldehydes, antioxidant activity, ethoxymethylene compounds, Schiff bases
DOI
10.7250/msac.2014.009

Tetere, Z., Zicāne, D., Rāviņa, I., Mieriņa, I., Rijkure, I. Synthesis and Antioxidant Properties of Novel Quinazoline Derivatives. Materiālzinātne un lietišķā ķīmija . Nr.30, 2014, 51.-54.lpp. ISSN 1407-7353. e-ISSN 2255-8713. Pieejams: doi:10.7250/msac.2014.009

Publikācijas valoda
English (en)