Self-Assembling Cationic Pyridine Derivatives NAD/NADH Analogues as Gene Deliverysystems: Biological and Physicochemical Properties

Drug Discovery Conference: Abstract Book 2015
Kārlis Pajuste, Martins Rucins, Oksana Petricenko, Aleksandra Vezane, Irena Timofejeva, Marina Gosteva, Klāvs Pajuste, Māra Plotniece, Brigita Cekavicus, Brigita Vigente, Tatjana Kozlovska, Arkadij Sobolev, Aiva Plotniece

Polyfunctional pyridinium derivatives on the 1,4-DHP scaffold possess self-assembling properties. 1,4-DHP deerivatives form liposomes and efficiently act as gene delivery agents. the influence of lipids head-group on transfection activity and properties of formed liposomes were studed.

Atslēgas vārdi
SELF-ASSEMBLING CATIONIC PYRIDINE DERIVATIVES, GENE DELIVERY
Hipersaite
http://www.innovabalt.eu/pictures/zinas/225.pdf

Pajuste, K., Rucins, M., Petricenko, O., Vezane, A., Timofejeva, I., Gosteva, M., Pajuste, K., Plotniece, M., Cekavicus, B., Vigente, B., Kozlovska, T., Sobolev, A., Plotniece, A. Self-Assembling Cationic Pyridine Derivatives NAD/NADH Analogues as Gene Deliverysystems: Biological and Physicochemical Properties. No: Drug Discovery Conference: Abstract Book, Latvija, Rīga, 27.-29. augusts, 2015. Rīga: 2015, 131.-131.lpp.

Publikācijas valoda
English (en)