Synthesis of 6-Perfluoroalkyl Analogues of Imatinib
Journal of Chemical Research 2015
S. Terentjeva, D. Muceniece, Viesturs Lūsis

6-Perfluoroalkyl pyrimidine derivatives of well known tyrosine kinase inhibitor imatinib have been synthesised from 1-(pyridin-3-yl)-3-perfluoroalkylbutane-1,3-diones by condensation with a 3-iodophenylguanidine and then by a Cu(I)-catalysed reaction with a 4-substituted benzamide.


Atslēgas vārdi
6-perfluoroalkyl analogues, imatinib
DOI
10.3184/174751915X14473498225894
Hipersaite
http://www.ingentaconnect.com/content/stl/jcr/2015/00000039/00000012/art00006

Terentjeva, S., Muceniece, D., Lūsis, V. Synthesis of 6-Perfluoroalkyl Analogues of Imatinib. Journal of Chemical Research, 2015, Vol.39, No.12, 701.-705.lpp. ISSN 1747-5198. Pieejams: doi:10.3184/174751915X14473498225894

Publikācijas valoda
English (en)
RTU Zinātniskā bibliotēka.
E-pasts: uzzinas@rtu.lv; Tālr: +371 28399196