Conjugate Addition of Aryl Nucleophiles to α,β-Unsaturated Cinnamic Acid Derivatives Containing Evans Type Chiral Auxiliaries

Tetrahedron: Asymmetry 2016
Zigmārs Leitis, Viesturs Lūsis

Cinnamides containing oxazolidin-2-one type auxiliaries have been prepared. A novel pathway to chiral 4-aryl-6-methyl-3,4-dihydrocoumrines via the asymmetric conjugate addition of arylmagnesium bromides to these cinnamides is described.

Atslēgas vārdi
aryl nucleophiles, α,β-unsaturated cinnamic acid derivatives
DOI
10.1016/j.tetasy.2016.07.003
Hipersaite
http://www.sciencedirect.com/science/article/pii/S0957416616301586

Leitis, Z., Lūsis, V. Conjugate Addition of Aryl Nucleophiles to α,β-Unsaturated Cinnamic Acid Derivatives Containing Evans Type Chiral Auxiliaries. Tetrahedron: Asymmetry, 2016, Vol.27, Iss.17-18, 843.-851.lpp. ISSN 0957-4166. Pieejams: doi:10.1016/j.tetasy.2016.07.003

Publikācijas valoda
English (en)